Most of the patients who suffer from this condition are elderly people but the good news is that this specific disease course is milder than dementia. Focusing on the differences between LANS and other progressive dementias such as Alzheimer’s places patients in a favorable position as memories are still present.

Main Outcomes of the Studies at Mayo Clinic:

Epidemiology and Pathogenesis of LANS: One of the defined forms of the disease characterizing age with emotional control is LANS which lies within the limbic area that controls the memory of a living being. The condition LANS is most specifically under the same symptoms as Alzheimer’s disease but that particular eye focuses on the stance that one is better off than patients of Alzheimer’s disease.

New Diagnostic Criteria: The only means of diagnosing the course of LANS has always been considered bone abnormalities on post mortem examinations. The need of the hour is the assistance of neurologists who place the existing clinical criteria to expedite the diagnosis of the disease. Some of the listed requirements are:

age and health determinant factors.

Severe loss of memory.

scans of the brain that show various limbic system imaging changes.

perturbations of some protein substances that are involved in neurodegenerative changes.

Research Basis: More than 200 patients’ data were collected, and materials from such large observational studies as ADNI, the Mayo Clinic Study of Aging, and the Mayo Clinic Alzheimer Disease Research Center were used for verification of the diagnostic criteria. This validation procedure guarantees the criteria’s reliability for clinical applications.

Implications for Patients: For patients who suffer from loss of memory but at a lesser severity than in Alzheimer’s disease, a new diagnosis, which is termed as LANS, is offered. Mayo Clinic Researchers’ more narrow definition allows physicians to be more efficient in:

At an early stage, identification and classification of the syndrome.

LANS and Alzheimer’s disease differentiation in order to administer more appropriate therapies.

Optimizing the information families have regarding prognoses for patients and their families.

The creation of such framework is indeed a breath of fresh air concerning the diagnosis of neurodegenerative conditions and therefore memory loss disorders as it is associated with advanced understanding and treatment of these conditions.